Below we integrate these principles with representative mechanisms and translational readouts, building on Biological Sources and Subcellular Compartments of ROSCrosstalk with RNS/RSS and iron sections and the manuscripts organizing framework
Both Pfizer and Moderna have developed bivalent vaccines containing ancestral SARS-CoV-2 and an Omicron variant
and J-S.A), ANR BETAPLASTICITY (ANR-17-CE14-0034 to J-S.A.), European Foundation for the Study of Diabetes (EFSD, to J-S.A.), INSERM, CNRS, Institut Pasteur de Lille (CPER CTRL Melodie, to E.C
This phenomenon can be caused by the fact that the released elemental mercury can be re-oxidized in the intracellular compartment by several enzymes, such as catalase [120,121] and re-enter the catalytic GSH-depleting cycle, ultimately leading to a displacement of the intracellular redox potential towards less negative, pro-apoptotic or necrotic values